RTI International

RTI International is an independent, nonprofit institute that provides research, development, and technical services to government and commercial clients worldwide.

ALA-ACRC

The American Lung Association - Airways Clinical Research Centers (ACRC) Network is the nation’s largest not-for-profit network of clinical centers dedicated to asthma and COPD research working to positively impacts patients through large patient-focused clinical trials led by some of the best investigators nationwide.

CCTRN

The Cardiovascular Cell Therapy Research Network (CCTRN) is a network of physicians, scientists, and support staff dedicated to studying stem cell therapy for treating heart disease.

CLOT

The Consortium Linking Oncology with Thrombosis (CLOT) encourages studies in selected cancer types that expand mechanistic investigation into the intersection between cancer and thrombotic pathways and applies mechanistic insights towards the identification and development of biomarkers of thrombotic risk or cancer progression.

CLOTT

The Consortium of Leaders in the study of Post-Traumatic Thromboembolism (CLOTT) focuses on the significance of incidentally discovered pulmonary thrombi after injury as well as the role of fibrinogen breakdown in the development of post-traumatic pulmonary embolism.

CTSN

The goal of the Cardiothoracic Surgical Trials Network (CTSN) is to foster a culture of rigorous scientific comparisons and to promote the evaluation of newer surgical techniques, devices, and innovative pharmaceutical and bioengineered products directed at improving cardiovascular disease outcomes in adult populations.

CTN

The Clinical Trials Network (CTN) provides an enterprise in which the National Institute of Drug Abuse (NIDA), treatment researchers, and community-based service providers work toward new treatment options in community-level clinical practice.

HFN

The Heart Failure Clinical Research Network (HFN) is a clinical research initiative funded by NHLBI with the aim of improving our understanding of the condition and to discover innovative treatment options.

I-SPY

The I-SPY series of trials are changing the way new treatment are developed for breast cancer, helping make available new, better, and more personalized treatments, faster.

INVESTED

Influenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure (INVESTED) is a multi-center, randomized, double blind, active-control trial of high dose influenza vaccine compared to standard dose influenza vaccine for three seasons in adult participants with a history of myocardial infarction or heart failure.

ISCHEMIA

The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) is an international comparative effectiveness study to determine the best way to manage stable ischemic heart disease.

IVY Network

The Influenza Vaccine Effectiveness in the Critically Ill (IVY) Network is a multi-site consortium of academic medical centers in the US funded by the Centers for Disease Control and Prevention (CDC) to conduct research on acute viral respiratory infections. 

LBCR

The Laboratory for Clinical Biochemistry Research (LCBR) at the University of Vermont – Learner College of Medicine focuses on understanding risk factors for heart disease, stroke, venous thrombosis, obesity, diabetes, aging, and frailty using a wide variety of assays in population and family-based research settings.

LITES

Linking Investigations in Trauma and Emergency Services (LITES) is a research network for traumatic brain injury, whole blood, airway management, and emergency medical services.

MHICC

The Montreal Heart Innovations Coordinating Center Network (MHICC) is dedicated to research in the fields of cardio-metabolic, renal, respiratory, oncology, cognitive function, gastro-intestinal, imaging, and precisions medicine.

Optumcare

Optumcare is a transformational force in the delivery of health care, integrating high-quality service across the ambulatory care continuum, offering local care powered by the strength of national resources, and delivering value-based care by scaling the most effective evidence-based medicine. 

PCCRG

Pragmatic Critical Care Research Group: Improving the care of critically ill adults by studying common critical care practices in the environment in which they occur.

STAR

The Stakeholders, Technology, and Research (STAR) Clinical Research Network robustly supports comparative effectiveness studies, pragmatic clinical trials, health system innovation, and the other research needs to improve health in the southern United States.

PETAL

The Clinical Trials Network for the Prevention and Early Treatment of Acute Lung Injury (PETAL) is a network of Clinical Centers (CC) and a Clinical Coordinating Center (CCC) funded by NHLBI to develop and conduct randomized controlled clinical trials to prevent or treat Acute Respiratory Distress Syndrome (ARDS).

PrecISE

The Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network is a network of medical centers, doctors, and scientists looking for better ways to treat teens and adults with severe asthma.

PREPARE

The Person Empowered Asthma Relief (PREPARE) study looks at two different ways to take medicines for rescue or quick relief of asthma symptoms among Latino or Hispanic patients and Black or African American patients.

PTC

The Pulmonary Trials Cooperative (PTC) was established by NHLBI to facilitate efficient “real world” research into chronic lung disease like interstitial lung disease, pulmonary hypertension, COPD, sarcoidosis, and obstructive sleep apnea.

RELIANCE

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) is nationwide trial, led by the COPD Foundation Patient Powered Research Network, to compare azithromycin and roflumilast to learn which works best for which patients.

REMAP-CAP

REMAP-CAP is a randomized, embedded, multi-factorial, adaptive platform trial for community-acquired pneumonia that can adapt to efficiently evaluate multiple treatment options for patients who are critically ill.

SIREN

The Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) is funded by the National Institute for Neurological Disorders and Stroke (NINDS), the National Center for Advancing Translational Science (NCATS), and NHLBI with the goal of improving the outcomes of patients with neurologic, cardiac, respiratory and hematologic emergencies by identifying effective treatments given in the earliest stages of care.

TACTIC

The Trans-Agency Consortium for Trauma-Induced Coagulopathy (TACTIC) was assembled to study coagulation in trauma patients.

TIMI

The Thrombolysis in Myocardial Infarction (TIMI) Study Group provides robust expertise in the key aspects of a clinical trial including academic leadership, global management, biostatistics, clinical event adjudication, safety desk, medical hotline, and core laboratories.